![]() ![]() The results of the work, led by Sharon L. Using a high-throughput screen for drugs developed by the research team, they discovered that auranofin - a drug approved by the US Food and Drug Administration 25 years ago for rheumatoid arthritis - is very effective in targeting an enzyme that protects amebae from oxygen attack (thus enhancing sensitivity of the amebae to reactive oxygen-mediated killing). ![]()
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